An effective tool for screening a large number of genetic sequences at once is known as A) FISH. B) microarray. C) cDNA synthesis. D) gel electrophoresis. E) restriction analysis.

An effective tool for screening a large number of genetic sequences at once is known as
A) FISH.
B) microarray.
C) cDNA synthesis.
D) gel electrophoresis.
E) restriction analysis.

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Answer

• B) microarray.
  Explanation:
  Microarrays consist of thousands of individual fragments of DNA, immobilized on a solid support that hybridize with complimentary sequences in the organism of interest. Fluorescent reporter molecule is used to detect the hybridization. Detection of different organisms can be achieved at once by using different probe sequences on a single microarray. This technique is considered a large-scale and a high-throughput screening technique. Each spot has different DNA, RNA or protein fragment, which come into contact with an unknown mixture with complimentary substances labelled with a dye. After hybridization, the amount of dye is quantified.